Obstructive sleep apnea as a risk factor for type 2 diabetes mellitus

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Obstructive sleep apnea as a risk factor for type 2 diabetes mellitus

Obstructive sleep apnea (OSA) is independently associated with cardiovascular and cardiometabolic risk in several large epidemiologic studies. OSA leads to several physiologic disturbances such as intermittent hypoxia, sleep fragmentation, and increase in autonomic tone. These disturbances have been associated with insulin resistance and type 2 diabetes mellitus (T2DM) in animal and human studi...

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CLINICAL RESEARCH STUDY Obstructive Sleep Apnea as a Risk Factor for Type 2 Diabetes

PURPOSE: Cross-sectional studies have documented the co-occurrence of obstructive sleep apnea (hereafter, sleep apnea) with glucose intolerance, insulin resistance, and type 2 diabetes mellitus (hereafter, diabetes). It has not been determined, however, whether sleep apnea is independently associated with the subsequent development of diabetes, accounting for established risk factors. METHODS: ...

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Obstructive sleep apnea and type 2 diabetes

Type 2 diabetes and obstructive sleep apnea (OSA) are diseases with high prevalence and major public health impact. There is evidence that regular snoring and OSA are independently associated with alterations in glucose metabolism. Thus, OSA might be a risk factor for the development of type 2 diabetes. Possible causes might be intermittent hypoxia and sleep fragmentation, which are typical fea...

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ژورنال

عنوان ژورنال: Nature and Science of Sleep

سال: 2015

ISSN: 1179-1608

DOI: 10.2147/nss.s90835